The Ritz Carlton is probably the best hotel at the moment together with the Hyatt. Location of the former is better. But look out for the new W Hotel (from May 2009) in Plaza Peru in El Golf and the Aubrey - Santiago's first boutique hotel which is opening soon (was planned for April 2009?) in Bellavista. Rumour also has it that the owners of the El Indigo in Puerto Natales are considering a boutique hotel in Vitacura. I have only stayed at the Ritz which is very good (apart from the building site on its front door step – the las Condes cultural centre due for completion in 2010). For longer stays the El Bosque Suites is best of the bunch of otherwise disappointing (apparently) aparthotels. I stayed there 4 weeks and it was perfectly OK and more affordable than the Ritz.